Trinity Medical Center I Dr. Marin Guentchev, MD, PhD



Ampoule with delayed-acting corticosteroid
Corticosteroids are anti-inflammatory drugs prescribed for a wide range of conditions PMID: 31568125. Corticosteroids, like urbasone, cortisone, hydrocortisone, and prednisolone, are drugs used in the treatment of edema, allergies, rashes, lupus, asthma, and others. These drugs may have serious side effects. Corticosteroids mimic the effect on hormones that the human body produces naturally in the adrenal glands.

Corticosteroids suppress inflammation. This can improve the symptoms of inflammatory conditions such as arthritis and asthma.

Corticosteroids can also suppress the immune system, which can help control autoimmune development (conditions in which the immune system mistakenly attacks tissue owners). Therefore, corticosteroids are used to suppress the immune system, to prevent organ transfer during transplants, and to treat rheumatoid arthritis, lupus, asthma, allergies, and many other conditions.

They are also used in Addison's disease, a condition in which the adrenal glands are unable to produce the minimum amount of corticosteroids the body needs.

Corticosteroids can be taken:

- by mouth in the form of tablets, capsules, or syrups
- by inhaler and intranasal spray. These forms help control the inflammation associated with asthma and nasal allergies.
- topically on the skin or mucous membranes.
- by intramuscular or intravenous injection.
- intraoperatively - on nerve structures

Side effects on systemic corticosteroid intake

Oral (oral) or injectable (intravenous or intramuscular) administration of corticosteroids spreads throughout the body. This route of administration is likely to cause significant side effects. Side effects depend on the dose of the drug and may include:

- Glaucoma (increased pressure in the eyes)
- Swelling - fluid retention causing swelling of the legs
- Hypertension - high blood pressure
- Mood, memory and other mental problems and other psychological effects such as confusion or delirium
- Weight gain, with fat deposits in the abdomen, face, and back of the neck
- Fungal infection in the mucous membranes

Chronic corticosteroid use can lead to:

- Cataract - a blurring of the lens in one or two eyes
- Diabetes - high blood sugar
- Increased risk of infections, especially in bacterial, viral, and fungal microorganisms
- Osteoporosis and contact her fractures
- Muscle atrophy

Side effects on topical corticosteroids

- Thinning of the skin
- Red skin
- Acne


The price of corticosteroids varies from a few stotinki for one tablet to several tens of levs for special parenteral medications.
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Trinity Medical Center
117 Zaichar St /Ground floor/
/Konstantin Velichkov Metro Station/
BG-1309 Sofia, Bulgaria
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