Spine literature: Utility of prolonged prophylactic systemic antibiotics for wound drains in posterior spine surgery: a systematic review and meta-analysis.

Summary (English)

Educational summary of peer-reviewed work on spinal disorders (not medical advice).

Article: Utility of prolonged prophylactic systemic antibiotics for wound drains in posterior spine surgery: a systematic review and meta-analysis.

Authors (excerpt): Gnel Pivazyan, Ziam Khan, Josef D Williams, Alexander J Kim, Deja M Rush

Overview: OBJECTIVE: Closed suction drains, often used after posterior spinal surgery, pose a potential risk of infection. To combat this risk, many surgeons opt for a prolonged prophylactic antibiotic regimen. Since 2015, several studies have shown that prolonged prophylactic systemic antibiotics (PPSA) for drains provides no additional benefit in reducing surgical site infection (SSI) rates. However, most of these studies lacked sufficient power to make reliable conclusions. To date, there has been no meta-analysis conducted to further investigate this issue. The aim of this study was to investigate whether a regimen of PPSA reduces the incidence of deep SSIs in adult patients with closed suction drains following posterior spinal surgeries. METHODS: The protocol of the current systematic review was registered with PROSPERO. A systematic review of the literature in PubMed (Medline), Europe PMC, Embase, and Cochrane Review databases was…

Full citation: Utility of prolonged prophylactic systemic antibiotics for wound drains in posterior spine surgery: a systematic review and meta-analysis.. Journal of neurosurgery. Spine. PubMed: PMID 36708541; DOI: 10.3171/2022.12.SPINE221218.

Consult the original paper for methods, statistics, and clinical applicability.

Summary (Bulgarian)

Това е обобщение за пациенти и специалисти, базирано на официалното резюме в PubMed. Публикацията е в списание Journal of neurosurgery. Spine и засяга теми, свързани с гръбначния стълб (диагностика, лечение или епидемиология — според съдържанието на оригиналната статия). Не замества очен преглед при лекар и не представлява персонализиран медицински съвет.

Заглавие: Spine literature: Utility of prolonged prophylactic systemic antibiotics for wound drains in posterior spine surgery: a systematic review and meta-analysis.

Оригинално резюме (английски, съкратено): OBJECTIVE: Closed suction drains, often used after posterior spinal surgery, pose a potential risk of infection. To combat this risk, many surgeons opt for a prolonged prophylactic antibiotic regimen. Since 2015, several studies have shown that prolonged prophylactic systemic antibiotics (PPSA) for drains provides no additional benefit in reducing surgical site infection (SSI) rates. However, most of these studies lacked sufficient power to make reliable conclusions. To date, there has been no meta-analysis conducted to further investigate this issue. The aim of this study was to investigate whether a regimen of PPSA reduces the incidence of deep SSIs in adult patients with closed suction drains following posterior spinal surgeries. METHODS: The protocol of the…

Source: Utility of prolonged prophylactic systemic antibiotics for wound drains in posterior spine surgery: a systematic review and meta-analysis.. Journal of neurosurgery. Spine. PubMed: PMID 36708541; DOI: 10.3171/2022.12.SPINE221218.