Spine literature: Surgery and stereotactic radiosurgery for spinal leiomyosarcoma: a single-institution retrospective series and systematic review.

Summary (English)

Educational summary of peer-reviewed work on spinal disorders (not medical advice).

Article: Surgery and stereotactic radiosurgery for spinal leiomyosarcoma: a single-institution retrospective series and systematic review.

Authors (excerpt): Aroosa Zamarud, Neelan J Marianayagam, Vashisht Sekar, Stefano Testa, David J Park

Overview: OBJECTIVE: Leiomyosarcoma (LMS) is a rare, aggressive soft-tissue sarcoma that seldom spreads to the bone. The spine can be either the site of LMS osseous metastases or the primary tumor site. The optimal treatment option for spinal LMS is still unclear. The authors present a cohort of patients with spinal LMS treated with either upfront surgery or upfront CyberKnife stereotactic radiosurgery (SRS). METHODS: The authors retrospectively studied the clinical and radiological outcomes of 17 patients with spinal LMS treated at their institution between 2004 and 2020. Either surgery or SRS was used as the upfront treatment. The clinical and radiological outcomes were assessed. A systematic review of the literature was also conducted. RESULTS: Of the 17 patients (20 spinal lesions), 12 (70.6%) were female. The median patient age was 61 years (range 41-80 years). Ten patients had upfront surgery for their spinal lesions, and 7 had…

Full citation: Surgery and stereotactic radiosurgery for spinal leiomyosarcoma: a single-institution retrospective series and systematic review.. Journal of neurosurgery. Spine. PubMed: PMID 38157539; DOI: 10.3171/2023.10.SPINE23666.

Consult the original paper for methods, statistics, and clinical applicability.

Summary (Bulgarian)

Това е обобщение за пациенти и специалисти, базирано на официалното резюме в PubMed. Публикацията е в списание Journal of neurosurgery. Spine и засяга теми, свързани с гръбначния стълб (диагностика, лечение или епидемиология — според съдържанието на оригиналната статия). Не замества очен преглед при лекар и не представлява персонализиран медицински съвет.

Заглавие: Spine literature: Surgery and stereotactic radiosurgery for spinal leiomyosarcoma: a single-institution retrospective series and systematic review.

Оригинално резюме (английски, съкратено): OBJECTIVE: Leiomyosarcoma (LMS) is a rare, aggressive soft-tissue sarcoma that seldom spreads to the bone. The spine can be either the site of LMS osseous metastases or the primary tumor site. The optimal treatment option for spinal LMS is still unclear. The authors present a cohort of patients with spinal LMS treated with either upfront surgery or upfront CyberKnife stereotactic radiosurgery (SRS). METHODS: The authors retrospectively studied the clinical and radiological outcomes of 17 patients with spinal LMS treated at their institution between 2004 and 2020. Either surgery or SRS was used as the upfront treatment. The clinical and radiological outcomes were assessed. A systematic review of the literature was also conducted. RESULTS: Of the 17 patients (20…

Source: Surgery and stereotactic radiosurgery for spinal leiomyosarcoma: a single-institution retrospective series and systematic review.. Journal of neurosurgery. Spine. PubMed: PMID 38157539; DOI: 10.3171/2023.10.SPINE23666.