Spine literature: PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation.

Summary (English)

Educational summary of peer-reviewed work on spinal disorders (not medical advice).

Article: PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation.

Authors (excerpt): Jacob Lønborg, Reza Jabbari, Muhammad Sabbah, Karsten T Veien, Matti Niemelä

Overview: BACKGROUND: The benefit of percutaneous coronary intervention (PCI) in patients with stable coronary artery disease and severe aortic stenosis who are undergoing transcatheter aortic-valve implantation (TAVI) remains unclear. METHODS: In an international trial, we randomly assigned, in a 1:1 ratio, patients with severe symptomatic aortic stenosis and at least one coronary-artery stenosis with a fractional flow reserve of 0.80 or less or a diameter stenosis of at least 90% either to undergo PCI or to receive conservative treatment, with all patients also undergoing TAVI. The primary end point was a major adverse cardiac event, defined as a composite of death from any cause, myocardial infarction, or urgent revascularization. Safety, including bleeding events and procedural complications, was assessed. RESULTS: A total of 455 patients underwent randomization: 227 to the PCI group and 228 to the conservative-treatment group. The…

Full citation: PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation.. The New England journal of medicine. PubMed: PMID 39216095; DOI: 10.1056/NEJMoa2401513.

Consult the original paper for methods, statistics, and clinical applicability.

Summary (Bulgarian)

Това е обобщение за пациенти и специалисти, базирано на официалното резюме в PubMed. Публикацията е в списание The New England journal of medicine и засяга теми, свързани с гръбначния стълб (диагностика, лечение или епидемиология — според съдържанието на оригиналната статия). Не замества очен преглед при лекар и не представлява персонализиран медицински съвет.

Заглавие: Spine literature: PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation.

Оригинално резюме (английски, съкратено): BACKGROUND: The benefit of percutaneous coronary intervention (PCI) in patients with stable coronary artery disease and severe aortic stenosis who are undergoing transcatheter aortic-valve implantation (TAVI) remains unclear. METHODS: In an international trial, we randomly assigned, in a 1:1 ratio, patients with severe symptomatic aortic stenosis and at least one coronary-artery stenosis with a fractional flow reserve of 0.80 or less or a diameter stenosis of at least 90% either to undergo PCI or to receive conservative treatment, with all patients also undergoing TAVI. The primary end point was a major adverse cardiac event, defined as a composite of death from any cause, myocardial infarction, or urgent revascularization. Safety, including bleeding events and…

Source: PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation.. The New England journal of medicine. PubMed: PMID 39216095; DOI: 10.1056/NEJMoa2401513.