Spine literature: Lower-Ischemic-Risk Profile of Coated Flow Redirection Endoluminal Device X Compared With Uncoated Flow Redirection Endoluminal Device Flow Diverter in the Treatment of Unruptured Intracranial Aneurysms.

Summary (English)

Educational summary of peer-reviewed work on spinal disorders (not medical advice).

Article: Lower-Ischemic-Risk Profile of Coated Flow Redirection Endoluminal Device X Compared With Uncoated Flow Redirection Endoluminal Device Flow Diverter in the Treatment of Unruptured Intracranial Aneurysms.

Authors (excerpt): Lukas Goertz, Sophia Hohenstatt, Dominik F Vollherbst, Hanna Styczen, Eberhard Siebert

Overview: BACKGROUND AND OBJECTIVES: Flow Redirection Endoluminal Device (FRED) X is a new generation flow diverter with an antithrombotic surface coating. This study compares the procedural safety and short-term efficacy of FRED X with its uncoated predecessor, the FRED. METHODS: Patients treated with FRED and FRED X devices for unruptured aneurysms between 2013 and 2023 at 3 neurovascular centers were retrospectively reviewed. The procedural ischemic event rate was the safety end point, and the complete aneurysm occlusion rate at 1 year was the efficacy end point. Multivariable regression adjustment and 1:1 propensity score matching were performed to control for potential confounding. RESULTS: The FRED X group (137 patients) had a higher prevalence of recurrent and bifurcation aneurysms and fewer aneurysms with branch involvement than the FRED X group (156 patients). The ischemic event rate was lower in FRED X (1/156 [0.6%]) than in FRED…

Full citation: Lower-Ischemic-Risk Profile of Coated Flow Redirection Endoluminal Device X Compared With Uncoated Flow Redirection Endoluminal Device Flow Diverter in the Treatment of Unruptured Intracranial Aneurysms.. Neurosurgery. PubMed: PMID 39471102; DOI: 10.1227/neu.0000000000003188.

Consult the original paper for methods, statistics, and clinical applicability.

Summary (Bulgarian)

Това е обобщение за пациенти и специалисти, базирано на официалното резюме в PubMed. Публикацията е в списание Neurosurgery и засяга теми, свързани с гръбначния стълб (диагностика, лечение или епидемиология — според съдържанието на оригиналната статия). Не замества очен преглед при лекар и не представлява персонализиран медицински съвет.

Заглавие: Spine literature: Lower-Ischemic-Risk Profile of Coated Flow Redirection Endoluminal Device X Compared With Uncoated Flow Redirection Endoluminal Device Flow Diverter in the Treatment of Unruptured Intracranial Aneurysms.

Оригинално резюме (английски, съкратено): BACKGROUND AND OBJECTIVES: Flow Redirection Endoluminal Device (FRED) X is a new generation flow diverter with an antithrombotic surface coating. This study compares the procedural safety and short-term efficacy of FRED X with its uncoated predecessor, the FRED. METHODS: Patients treated with FRED and FRED X devices for unruptured aneurysms between 2013 and 2023 at 3 neurovascular centers were retrospectively reviewed. The procedural ischemic event rate was the safety end point, and the complete aneurysm occlusion rate at 1 year was the efficacy end point. Multivariable regression adjustment and 1:1 propensity score matching were performed to control for potential confounding. RESULTS: The FRED X group (137 patients) had a higher prevalence of recurrent and…

Source: Lower-Ischemic-Risk Profile of Coated Flow Redirection Endoluminal Device X Compared With Uncoated Flow Redirection Endoluminal Device Flow Diverter in the Treatment of Unruptured Intracranial Aneurysms.. Neurosurgery. PubMed: PMID 39471102; DOI: 10.1227/neu.0000000000003188.