Spine literature: Effect of high disease activity on spinal sagittal malalignment in patients with rheumatoid arthritis.

Summary (English)

Educational summary of peer-reviewed work on spinal disorders (not medical advice).

Article: Effect of high disease activity on spinal sagittal malalignment in patients with rheumatoid arthritis.

Authors (excerpt): Shintaro Honda, Koichi Murata, Shunsuke Fujibayashi, Bungo Otsuki, Takayoshi Shimizu

Overview: OBJECTIVE: Atlantoaxial subluxation is a well-known serious complication encountered in patients with rheumatoid arthritis (RA). However, it is unknown whether RA affects global spinal alignment. The aim of this study was to investigate whether high disease activity in patients with RA exacerbates spinal sagittal malalignment. METHODS: The authors included 197 patients with RA who were followed up for > 2 years; standing spinal radiographs were obtained in all patients. Patients were divided into persistent moderate disease activity/high disease activity (pMDA/HDA; n = 64) and non-pMDA/HDA (n = 133) groups based on the disease activity at follow-up visits. Radiographic parameters assessed included pelvic incidence, pelvic tilt (PT), lumbar lordosis (LL), thoracic kyphosis (TK), and C7 sagittal vertical axis (SVA). RESULTS: Over an average 5-year follow-up, increases in SVA, PT, and TK and a decrease in LL were observed. The…

Full citation: Effect of high disease activity on spinal sagittal malalignment in patients with rheumatoid arthritis.. Journal of neurosurgery. Spine. PubMed: PMID 38552241; DOI: 10.3171/2024.1.SPINE231199.

Consult the original paper for methods, statistics, and clinical applicability.

Summary (Bulgarian)

Това е обобщение за пациенти и специалисти, базирано на официалното резюме в PubMed. Публикацията е в списание Journal of neurosurgery. Spine и засяга теми, свързани с гръбначния стълб (диагностика, лечение или епидемиология — според съдържанието на оригиналната статия). Не замества очен преглед при лекар и не представлява персонализиран медицински съвет.

Заглавие: Spine literature: Effect of high disease activity on spinal sagittal malalignment in patients with rheumatoid arthritis.

Оригинално резюме (английски, съкратено): OBJECTIVE: Atlantoaxial subluxation is a well-known serious complication encountered in patients with rheumatoid arthritis (RA). However, it is unknown whether RA affects global spinal alignment. The aim of this study was to investigate whether high disease activity in patients with RA exacerbates spinal sagittal malalignment. METHODS: The authors included 197 patients with RA who were followed up for > 2 years; standing spinal radiographs were obtained in all patients. Patients were divided into persistent moderate disease activity/high disease activity (pMDA/HDA; n = 64) and non-pMDA/HDA (n = 133) groups based on the disease activity at follow-up visits. Radiographic parameters assessed included pelvic incidence, pelvic tilt (PT), lumbar lordosis (LL), thoracic…

Source: Effect of high disease activity on spinal sagittal malalignment in patients with rheumatoid arthritis.. Journal of neurosurgery. Spine. PubMed: PMID 38552241; DOI: 10.3171/2024.1.SPINE231199.