Spine literature: Comparison of PED/PED Flex and PED Shield in the treatment of unruptured intracerebral aneurysms.

Summary (English)

Educational summary of peer-reviewed work on spinal disorders (not medical advice).

Article: Comparison of PED/PED Flex and PED Shield in the treatment of unruptured intracerebral aneurysms.

Authors (excerpt): Kareem El Naamani, Panagiotis Mastorakos, Clifford J Yudkoff, Rawad Abbas, Stavropoula I Tjoumakaris

Overview: OBJECTIVE: The object of this study was to compare the efficacy and safety profile of the Pipeline embolization device (PED)/Pipeline Flex embolization device (PED Flex) with that of the Pipeline Flex embolization device with Shield Technology (PED Shield). After introducing the first-generation PED and the second-generation PED Flex with its updated delivery system, the PED Shield was launched with a synthetic layer of phosphorylcholine surface modification to reduce thrombogenicity. METHODS: This is a retrospective review of unruptured aneurysms treated with PED/PED Flex versus PED Shield between 2017 and 2022 at the authors' institution. Patients with ruptured aneurysms, adjunctive treatment, failed flow diverter deployment, and prior treatment of the target aneurysm were excluded. Baseline characteristics were collected for all patients, including age, sex, past medical history (hypertension, hyperlipidemia, diabetes mellitus),…

Full citation: Comparison of PED/PED Flex and PED Shield in the treatment of unruptured intracerebral aneurysms.. Journal of neurosurgery. PubMed: PMID 37877979; DOI: 10.3171/2023.7.JNS23981.

Consult the original paper for methods, statistics, and clinical applicability.

Summary (Bulgarian)

Това е обобщение за пациенти и специалисти, базирано на официалното резюме в PubMed. Публикацията е в списание Journal of neurosurgery и засяга теми, свързани с гръбначния стълб (диагностика, лечение или епидемиология — според съдържанието на оригиналната статия). Не замества очен преглед при лекар и не представлява персонализиран медицински съвет.

Заглавие: Spine literature: Comparison of PED/PED Flex and PED Shield in the treatment of unruptured intracerebral aneurysms.

Оригинално резюме (английски, съкратено): OBJECTIVE: The object of this study was to compare the efficacy and safety profile of the Pipeline embolization device (PED)/Pipeline Flex embolization device (PED Flex) with that of the Pipeline Flex embolization device with Shield Technology (PED Shield). After introducing the first-generation PED and the second-generation PED Flex with its updated delivery system, the PED Shield was launched with a synthetic layer of phosphorylcholine surface modification to reduce thrombogenicity. METHODS: This is a retrospective review of unruptured aneurysms treated with PED/PED Flex versus PED Shield between 2017 and 2022 at the authors' institution. Patients with ruptured aneurysms, adjunctive treatment, failed flow diverter deployment, and prior treatment of the target…

Source: Comparison of PED/PED Flex and PED Shield in the treatment of unruptured intracerebral aneurysms.. Journal of neurosurgery. PubMed: PMID 37877979; DOI: 10.3171/2023.7.JNS23981.