Spine literature: Clinical features, radiological findings, and outcome in patients with symptomatic mild carotid stenosis: a MUSIC study.

Summary (English)

Educational summary of peer-reviewed work on spinal disorders (not medical advice).

Article: Clinical features, radiological findings, and outcome in patients with symptomatic mild carotid stenosis: a MUSIC study.

Authors (excerpt): Daina Kashiwazaki, Kohei Chida, Kazumichi Yoshida, Kiyofumi Yamada, Motohiro Morioka

Overview: OBJECTIVE: Plaque composition, but not degree of stenosis, may play a key role in the development of recurrent ischemic events in patients with symptomatic mild (< 50%) carotid artery stenosis. This multicenter prospective cohort study was aimed to determine their clinical and radiological features and to evaluate the benefits of carotid endarterectomy (CEA) for them. METHODS: This study included 124 patients with cerebrovascular or retinal ischemic events ipsilateral to mild carotid stenosis. Best medical therapy (BMT) was administered to all participants. CEA or carotid artery stenting was implemented at each institution's discretion. Baseline and 6-, 12-, and 24-month follow-up data were collected. The primary endpoint was ipsilateral ischemic stroke. Secondary endpoints included any stroke, ipsilateral transient ischemic attack, ipsilateral ocular symptoms, any death, and plaque progression requiring CEA/carotid artery…

Full citation: Clinical features, radiological findings, and outcome in patients with symptomatic mild carotid stenosis: a MUSIC study.. Journal of neurosurgery. PubMed: PMID 40601988; DOI: 10.3171/2024.10.JNS241185.

Consult the original paper for methods, statistics, and clinical applicability.

Summary (Bulgarian)

Това е обобщение за пациенти и специалисти, базирано на официалното резюме в PubMed. Публикацията е в списание Journal of neurosurgery и засяга теми, свързани с гръбначния стълб (диагностика, лечение или епидемиология — според съдържанието на оригиналната статия). Не замества очен преглед при лекар и не представлява персонализиран медицински съвет.

Заглавие: Spine literature: Clinical features, radiological findings, and outcome in patients with symptomatic mild carotid stenosis: a MUSIC study.

Оригинално резюме (английски, съкратено): OBJECTIVE: Plaque composition, but not degree of stenosis, may play a key role in the development of recurrent ischemic events in patients with symptomatic mild (< 50%) carotid artery stenosis. This multicenter prospective cohort study was aimed to determine their clinical and radiological features and to evaluate the benefits of carotid endarterectomy (CEA) for them. METHODS: This study included 124 patients with cerebrovascular or retinal ischemic events ipsilateral to mild carotid stenosis. Best medical therapy (BMT) was administered to all participants. CEA or carotid artery stenting was implemented at each institution's discretion. Baseline and 6-, 12-, and 24-month follow-up data were collected. The primary endpoint was ipsilateral ischemic stroke. Secondary…

Source: Clinical features, radiological findings, and outcome in patients with symptomatic mild carotid stenosis: a MUSIC study.. Journal of neurosurgery. PubMed: PMID 40601988; DOI: 10.3171/2024.10.JNS241185.