Spine literature: Angiography-Derived Fractional Flow Reserve to Guide PCI.

Summary (English)

Educational summary of peer-reviewed work on spinal disorders (not medical advice).

Article: Angiography-Derived Fractional Flow Reserve to Guide PCI.

Authors (excerpt): William F Fearon, Allen Jeremias, Guy Witberg, Rasha Al-Lamee, David J Cohen

Overview: BACKGROUND: Assessing intermediate coronary lesions with an intracoronary pressure wire improves clinical outcomes in patients undergoing cardiac catheterization and percutaneous coronary intervention (PCI). However, clinical use of pressure-wire-based physiological assessment remains low. Measurement of fractional flow reserve (FFR) derived from coronary angiographic images alone correlates well with pressure-wire-based FFR measurements and may simplify procedures, but its effect on clinical outcomes is unknown. METHODS: In this international noninferiority trial, we randomly assigned patients undergoing coronary angiography who were found to have at least one intermediate coronary stenosis to physiological assessment with measurements derived from angiographic images (FFRangio) or with pressure-wire-based measurements. The primary end point was a composite of death, myocardial infarction, or unplanned, clinically indicated…

Full citation: Angiography-Derived Fractional Flow Reserve to Guide PCI.. The New England journal of medicine. PubMed: PMID 41910384; DOI: 10.1056/NEJMoa2600949.

Consult the original paper for methods, statistics, and clinical applicability.

Summary (Bulgarian)

Това е обобщение за пациенти и специалисти, базирано на официалното резюме в PubMed. Публикацията е в списание The New England journal of medicine и засяга теми, свързани с гръбначния стълб (диагностика, лечение или епидемиология — според съдържанието на оригиналната статия). Не замества очен преглед при лекар и не представлява персонализиран медицински съвет.

Заглавие: Spine literature: Angiography-Derived Fractional Flow Reserve to Guide PCI.

Оригинално резюме (английски, съкратено): BACKGROUND: Assessing intermediate coronary lesions with an intracoronary pressure wire improves clinical outcomes in patients undergoing cardiac catheterization and percutaneous coronary intervention (PCI). However, clinical use of pressure-wire-based physiological assessment remains low. Measurement of fractional flow reserve (FFR) derived from coronary angiographic images alone correlates well with pressure-wire-based FFR measurements and may simplify procedures, but its effect on clinical outcomes is unknown. METHODS: In this international noninferiority trial, we randomly assigned patients undergoing coronary angiography who were found to have at least one intermediate coronary stenosis to physiological assessment with measurements derived from angiographic…

Source: Angiography-Derived Fractional Flow Reserve to Guide PCI.. The New England journal of medicine. PubMed: PMID 41910384; DOI: 10.1056/NEJMoa2600949.